Checklist for Diagnosing EoE
2018 AGREE Consensus
Diagnostic Criteria for EoE1
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(criteria you selected shown in purple)
Symptoms
Difficulty swallowing, chest pains, and comorbidity of food allergy to shellfish all reflect a clinical presentation suggestive of EoE
Endoscopic Assessment
Recent food impaction and EREFS total score of 5 out of 8 reflect upper endoscopic findings, which increase suspicion for EoE
Histologic Assessment
Esophageal eosinophilia of 40 eos/hpf is above the 15 eos/hpf threshold necessary to confirm EoE diagnosis
Exclusion of
Non-EoE Disorders
Lack of GERD excludes a common non-EoE disorder that may be present in patients with EoE
ALL of the Diagnostic Criteria are needed to confirm an EoE diagnosis,
including requiring esophageal biopsies to assess eosinophil count1
Case based on hypothetical patient.
AGREE, A Working Group on PPI-REE; EoE, eosinophilic esophagitis; PPI-REE, proton pump inhibitor-responsive esophageal eosinophilia.
1. Dellon ES, et al. Gastroenterology.
2018;155(4):1022-1033.